Tirosint® Direct Program

Tirosint® Direct is a convenient program based on a network of participating mail order pharmacies for Tirosint (levothyroxine sodium) capsules and Tirosint-SOL (levothyroxine sodium) oral solution. With the Tirosint Direct Program you can be confident that you will pay the lowest out-of-pocket cash price for your prescribed therapy depending on your individual circumstances.

Has your insurance company increasing your copay? Do you have a high insurance deductible for your medication or have no insurance? By using one of our participating Tirosint Direct Program mail order pharmacies, you will get your medication for a cash price of $65 for one month of therapy (30-day supply) or $170 for 3 months of therapy (a 90-day supply)* regardless of your insurance coverage. If you have health insurance, the pharmacy will give you a choice of paying the cash price or using your insurance and paying a copay which can be further reduced by using our Copay Savings Card. Go to the “Ways to Save” page to learn more about the Copay Savings Card.

*Prices subject to change.

For more details, mention the Tirosint Direct Program to your doctor or contact a participating Tirosint Direct pharmacy today.

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Benefits of Tirosint® Direct

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Easy Access

All patients are eligible to use the Tirosint Direct Program regardless of their insurance coverage status.

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Transparent Pricing

Through Tirosint Direct you can be confident that you will pay the lowest out-of-pocket cash price for either a Tirosint or Tirosint-SOL prescription depending on your individual circumstances. To learn the current cash price for your prescription contact a Tirosint Direct participating pharmacy today.

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Flexible Supply

You can get up to 180 days of therapy at a time thru Tirosint Direct. Note that prices are based on cartons of 30 gel caps each.

  • One Month Supply (1 carton; 30 days therapy)
  • Two Month Supply (2 cartons; 30 days of therapy per carton)
  • Three Month Supply (3 cartons; 30 days of therapy per carton)
  • Six Month Supply (6 cartons; 30 days of therapy per carton)

If you have questions about the supply you would like to purchase and its price, your Tirosint Direct pharmacy will be happy to help you.

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Available Doses & Fast Delivery

With Tirosint Direct you can be assured that you can always get your prescribed dose of Tirosint or Tirosint-SOL.  Tirosint Direct pharmacies stock all doses which are available for immediate delivery.

In most cases your medication will arrive within 2-3 business days after your order has been processed.

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Payment Options

All major credit cards are accepted. You can get a receipt that you can submit to your flexible spending account (FSA) or health savings account (HSA) administrator or your health insurer.

Using Tirosint® Direct for the First Time

When you participate in the Tirosint Direct Program:

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Your doctor submits your Tirosint prescription by faxing or electronically transmitting your prescription to one of Tirosint Direct’s participating pharmacies.

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After your prescription has been transmitted to one of Tirosint Direct’s mail order pharmacies, you will be contacted by phone to verify your name, address, and credit card information to cover the cash portion of your prescription. In most cases, you will receive a call within 24 hours. Customer service representatives will be available to answer your questions and to explain the process.

Cost Plus Drugs contacts patients only by email when we receive an Rx. The Rx must include the patient’s email address OR the patient must create an account on costplusdrugs.com before the Rx is sent. Otherwise, we will have no way to contact the patient. 

Now offering an online ordering
option for patients paying cash!

For patients who don’t require a benefit investigation and want to order online with cash, a convenient program with home delivery is now available. Prescriptions can be sent via e-prescribing or fax to Vytal (AmeriPharm/DBA Medvantx) and you can order refills, check your order status and request new prescriptions on our online ordering website.

Start your online order

Tirosint Direct Pharmacies Include:

Ships to all 50 states



Mark Cuban Cost Plus Drugs

Ships to all 50 states


Delta Logo

Ships to select US states



Ships to all 50 states

Toll free: 855-894-4441
Local: 601-268-6033

Sterling Logo

Ships to all 50 states and Puerto Rico.


Also available thru TPS Transition Pharmacy. Go to www.transitionrx.pharmacy

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Frequently Asked Questions

Why use Tirosint® Direct?

Participating pharmacies will offer you the lowest out-of-pocket cost to fill your prescription whether or not you have commercial health insurance.

What if I don’t have commercial health insurance?

If you don’t have insurance you will be offered the lowest cash cost available for your prescription. To learn the current cash price for Tirosint ,or Tirosint-SOL, contact one of the participating Tirosint Direct pharmacies.

How will I get my medication?

It usually takes 2-3 business days after your order has been processed to arrive at your door.

For Cost Plus Drugs
• Turnaround time depends on the shipping speed that the user selects at checkout. 
• All orders take 48 hours to be processed and filled. 
• After the order is filled, standard shipping is 5-7 business days; expedited shipping is 3-5 business days. 

How much will I pay using Tirosint Direct?

Patients paying cash pay as little as $170 for a 90-day prescription (3 cartons for $170) or $65 for a 30-day prescription (1 carton for $65)

Will my health insurance cover this?

Our participating pharmacies will work with your insurance provider and physician to determine your eligibility for commercial health insurance coverage. If you have commercial insurance coverage you will be given the option to use a Tirosint or Tirosint-SOL copay savings card that may help to further reduce your out-of pocket cost.