Levothyroxine is a hormone medication that is used to treat hypothyroidism, or an underactive thyroid. It is administered to replace or provide more of the thyroid hormone, which is normally produced by the thyroid gland.1 Once you have been prescribed levothyroxine, you will need to take it every day as your doctor directs. Only your doctor can prescribe levothyroxine.

Most medications used to treat hypothyroidism are tablets. In addition to levothyroxine, they contain a variety of excipients (inert ingredients) such as wheat starch (gluten), lactose, sugars, dyes and talc. These can sometimes cause irritation or make it harder for your body to absorb your thyroid medicine. The unique formulation of Tirosint helps to avoid these problems. Read on to discover why Tirosint may be a better option for you.2,3

See the list below of excipients commonly found in levothyroxine tablets.

Common excipients

  • Modified wheat starch (gluten)
  • Lactose monohydrate
  • Dyes
  • Confectioners’ sugar (contains corn starch)
  • Microcrystaline cellulose
  • Butylated hydroxyanisole (BHA)
  • Talc
  • Croscarmellose sodium
  • Calcium phosphate dibasic
  • Colloidal silicon dioxide
  • Mannitol
  • Crospovidone
  • Magnesium stearate
  • Acacia
  • Sucrose
  • Povidone
  • Sodium lauryl sulfate


Everyone is paying closer attention to the ingredients found in the foods we consume these days, so it only makes sense to do the same with medication. For people with serious food allergies or restrictions, exposure to even small quantities of certain ingredients may cause a serious reaction.4 In a recent survey of nearly 1,000 patients taking levothyroxine to treat their hypothyroidism, 15% of respondents reported allergies to the excipients commonly found in levothyroxine tablets.5

For people with food or ingredient sensitivities, Tirosint offers effective relief of hypothyroidism without sugars, dyes, alcohol, wheat starch (gluten), lactose, or any other excipients (inert ingredients) used to make traditional levothyroxine tablets. It is produced in a dedicated facility, where no other products are made, eliminating the risk of cross contamination and providing you with additional peace of mind.6


The story doesn’t end there. People who have gastrointestinal (GI) diseases or who are taking certain medications can have problems with consistently absorbing levothyroxine therapy. Tirosint has been clinically shown to be less affected by some stomach medications like proton pump inhibitors (Prilosec, Protonix, Nexium*) than tablet formulations of levothyroxine. For some patients this means that Tirosint may offer more consistent control of hypothyroid symptoms than similar doses of levothyroxine tablets. Simply stated, Tirosint does not contain excipients that can interfere with how well your body absorbs your thyroid medication, which ultimately can affect how well you feel.4

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