Levothyroxine is a hormone medication that is used to treat hypothyroidism, or an underactive thyroid. It is administered to replace or provide more of the thyroid hormone, which is normally produced by the thyroid gland.1 Once you have been prescribed levothyroxine, you will need to take it every day as your doctor directs. Only your doctor can prescribe levothyroxine.

Most medications used to treat hypothyroidism are tablets. In addition to levothyroxine, they contain a variety of excipients (inert ingredients) such as wheat starch (gluten), lactose, sugars, dyes and talc. These can sometimes cause irritation or make it harder for your body to absorb your thyroid medicine. The unique formulation of Tirosint helps to avoid these problems. Read on to discover why Tirosint may be a better option for you.2,3

Tirosint Packaging

See the list below of excipients commonly found in levothyroxine tablets.

Common excipients

  • Modified wheat starch (gluten)
  • Lactose monohydrate
  • Dyes
  • Confectioners’ sugar (contains corn starch)
  • Microcrystaline cellulose
  • Butylated hydroxyanisole (BHA)
  • Talc
  • Croscarmellose sodium
  • Calcium phosphate dibasic
  • Colloidal silicon dioxide
  • Mannitol
  • Crospovidone
  • Magnesium stearate
  • Acacia
  • Sucrose
  • Povidone
  • Sodium lauryl sulfate

Tolerability

Everyone is paying closer attention to the ingredients found in the foods we consume these days, so it only makes sense to do the same with medication. For people with serious food allergies or restrictions, exposure to even small quantities of certain ingredients may cause a serious reaction.4 In a recent survey of nearly 1,000 patients taking levothyroxine to treat their hypothyroidism, 15% of respondents reported allergies to the excipients commonly found in levothyroxine tablets.5

For people with food or ingredient sensitivities, Tirosint offers effective relief of hypothyroidism without sugars, dyes, alcohol, wheat starch (gluten), lactose, or any other excipients (inert ingredients) used to make traditional levothyroxine tablets. It is produced in a dedicated facility, where no other products are made, eliminating the risk of cross-contamination and providing you with additional peace of mind.6

Consistency

The story doesn’t end there. People who have gastrointestinal (GI) diseases or who are taking certain medications can have problems with consistently absorbing levothyroxine therapy. Tirosint has been clinically shown to be less affected by some stomach medications like proton pump inhibitors (Prilosec, Protonix, Nexium*) than tablet formulations of levothyroxine. For some patients this means that Tirosint may offer more consistent control of hypothyroid symptoms than similar doses of levothyroxine tablets. Simply stated, Tirosint does not contain excipients that can interfere with how well your body absorbs your thyroid medication, which ultimately can affect how well you feel.4

*Trademarks the property of their respective owners.

Who can benefit from Tirosint?

The first step in your journey to feeling better is to talk with your doctor. It is important that you accurately describe your symptoms and provide complete detail about your other medical conditions, other medications or supplements that you take, (both prescription and non-prescription) and your diet. Many patients don’t tell their doctors about the nutritional supplements that they take, but as you’ll discover, even the most common dietary items problems for your thyroid medication can make your treatment less effective.

The following tools have been created to help you to give your doctor the information that he/she will need to determine the right hypothyroidism treatment for you:5

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  • Excipients, or inactive ingredients found in levothyroxine tablets that may cause irritation.
  • Gastrointestinal (GI) conditions such as gastrointestinal reflux disorder (GERD), celiac disease, inflammatory bowel disease and other disorders and their treatments that can affect how well thyroid medication is absorbed.

Excipients (inactive ingredients) in levothyroxine tablets

Everyone is paying closer attention to the ingredients found in the foods we consume these days, so it only makes sense to do the same with medication. For people with serious food allergies or restrictions, exposure to even small quantities of certain ingredients may cause a serious reaction.5 In a recent survey of nearly 1,000 patients taking levothyroxine to treat their hypothyroidism, 15% of respondents reported allergies to the excipients commonly found in levothyroxine tablets.6

For people with food allergies and ingredient sensitivities, Tirosint capsules can offer effective relief of hypothyroidism without wheat starch (gluten), lactose, food dyes, and sugars used to make traditional levothyroxine tablets—Tirosint gel caps contain only 4 simple ingredients.8 Tirosint gel caps are produced in a dedicated facility, where no other products are made, eliminating the risk of cross contamination from ingredients that may be used to make other medications.7

Here is a partial list of excipients sometimes used to manufacture thyroid medications:8

  • Modified wheat starch (gluten)
  • Confectioners’ sugar (contains cornstarch)
  • Lactose monohydrate
  • Dyes

See excipients commonly used in the making of levothyroxine medications

Common excipients

Gastrointestinal (GI) conditions

GI conditions and the medications used to treat them can affect the way your body dissolves and absorbs a traditional levothyroxine tablet. Some conditions, such as celiac disease or lactose intolerance, may be aggravated by the excipients commonly found in levothyroxine tablets.4 Certain conditions or their treatments can alter the acid level in your stomach, which may impact how well you are able to absorb levothyroxine from a tablet. Under laboratory conditions, the effectiveness of Tirosint has been proven to be unaffected by changes in gastric acid level, unlike levothyroxine tablets.9

Many patients with GI conditions take a medication called a protein pump inhibitor (PPI).5 Brand name PPI medications include Prilosec, Protonix and Nexium*. A recent study has shown that taking a PPI can have a significant effect on the absorption of levothyroxine tablets. Tirosint  was shown to be less affected by the presence of a PPI.7,10

Make sure to tell your doctor if you have any of the above GI conditions or if you take medications like PPIs.5 If you and your physician determine that you are experiencing tolerability or malabsorption problems that stem from your current thyroid medication, it may be the result of taking GI medication that can interfere with your treatment. Perhaps it’s time to try Tirosint?

Commonly used medicines and dietary supplements that can affect levothyroxine therapy

Color-coded cartons

There are twelve different dosage strengths of Tirosint. This enables your doctor to prescribe the exact dosage that is right for you.

Each Tirosint carton is color-coded for each dosage strength and each capsule is labeled with a letter code, to make it easier for you and your pharmacy to ensure that you get the same dosage of Tirosint that your doctor has prescribed.7

Tirosint packaging

See the precise processes used to manufacture each Tirosint gel cap

Tirosint is made in Switzerland to the highest quality standards. It is manufactured in a facility that is dedicated to its production, where no other products are made. This eliminates the risk of cross-contamination and provides you with additional peace of mind.7

*Trademarks the property of their respective owners.